Stem cells and Fibroblast Growth Factor
Stem cells are responsible for replenishing cells that die each day and the body has about 5 Billion to 200 Million-Trillion cells. Stem cells can multiply or develop into any one of various kinds of cells such as blood, skin, hair, cells, & cell tissues that make an organ.
Embryonic & Adult Stem Cell
During the development of a fetus (embryonic stage), we have the “embryonic stem cells” or ES. This enables the fetus to form the different parts of the infant’s body. When the baby begins to grow and eventually develop into an adult, ES dissipates. However, the stem cells are not totally gone because cellular repair remains constant.
The Stem Cell Architect
Our body maintains “adult stem cells” that replenish blood cells, repair tissues, muscles, and influence hormone balance. But this too dissipates as we get much older. Thus the need for stem cell therapy came about. However, prior to infusing the body with fresh stem cells, Fibroblast Growth Factor or FGF, a signaling molecule, is needed to connect amino acids with these cells. Laminine contains both FGF and the full chain of amino acids.
Adult stem cells have limited abilities compared to ES. Furthermore, there is no need for ES to proliferate, given that the infant has now grown, with its brain, heart, kidney, liver, and other important parts fully developed. If we still had ES, we would likely be immortal.
Stem cell decline:
But as finite mortals, scientist began looking for ES elsewhere (such as pluripotent cells) and reintroducing it to the body to repair itself. It may not have the same effect but nonetheless have proven to affect the regeneration of cells and organs in a limited capacity.
The adult stem cell works well if cell tissue or organ that was damaged is minimal. However, as we age further, adult stem cells declines and cell regeneration is no longer efficient. (NCBI)
Laminine relation to stem cell therapy
Sources of stem cells
The most common source of stem cell is by extracting it from the human bone marrow and reintroducing it to the body. The process is painful and expensive.
Other sources are from a human embryonic cell (fetus) whose developing organs and tissues contain large amounts of stem cells, but it is not only controversial but unethical even if it was fertilized through in vitro. The umbilical cord is also a good source of these cells but nonetheless are still expensive procedures.
Pluripotent Stem Cells
Pluripotent Stem Cells or PSC is called “master cells” because they can produce other cells from our three basic body layers. These are the Ectoderm (Skin & Nervous System), Endoderm (Gastrointestinal, respiratory, glands, liver, and pancreas), Mesoderm (bone, cartilage, circulatory, muscles, etc). The PSC can potentially produce any cell or tissue the body needs to repair itself.
Alternative: Role of FGF in stem cell therapy
Instead of sourcing pluripotent cells from the bone marrow or the human embryo, an avian embryo can provide protein called Fibroblast Growth Factor or FGF. Laminine’s young tissue extract (YTE) called Fertilized Avian Egg Extract (FAEE) contains FGF.
Effects of Laminine in pre-diabetic patients
Stem cell architect – FGF
FGF acts in an autocrine or a paracrine manner interacting with its specific receptors and has been shown to play an important role in tissue formation. When a person undergoes stem cell therapy, his body is first injected with Fibroblast Growth Factor. FGF plays a very crucial role in order for the stem cell to work. FGF directs the stem cell where to go and what to repair, likened to an architect.
Understanding stem cells, FGF, & amino-acids connection
There are cell organs in our body that stem-cells cannot regenerate. Although stem cells can create billions of cells each day to replenish dead blood cells, it may not repair the heart or pancreas although it can repair small muscle tissues or nerves. This is where strengthening stem cell production helps.
The significant action of Fibroblast Growth Factor
Why we need FGF & amino acids
FGF directs stem cells and it needs amino acid proteins to do that. Amino acids are the building blocks of proteins and proteins are the building blocks of stem-cells. Thus, FGF and amino acid (proteins and peptides) function together to instigate cellular tissue repair.
Bottom line, we need these FGFs and amino acids in the body and the Laminine stem cell connection is a very good option. Taking a minimum dosage of 2-capsules per day can make a difference.